NCBI
National Center for
Biotechnology Information
Search
3HFG:
Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Sulfonyl-piperazine Inhibitor
PDB ID:
3HFG
Download
MMDB ID:
77030
PDB Deposition Date:
2009/5/11
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3HFG: dimeric; determined by author and by software (PISA)
Molecular Components in 3HFG
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Corticosteroid 11-beta-dehydrogenase Isozyme 1
(Gene symbol:
HSD11B1
)
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine
2
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303